Technical University of Munich (TUM)
Department of Nutrition and Immunology
How has the PreciPoint M8 microscope transformed the way you research?
With the M8, we have an overview of the slide immediately at high resolution magnification. The digital microscope is much quicker and we have a better orientation. Now, it’s possible to zoom into our areas of interest and to know exactly where we are on the slide.
Prior to the M8, we used a traditional microscope with a camera on the top that exported the pictures onto a computer. It could only take one image at the magnification of the objective, so for an overview, we took the picture at 10x objective, then changed the objective to a higher magnification for specific areas. Also to zoom in and out of particular sections, we needed to change objectives and repeat the process. This took much longer, perhaps even double the time.
What are some ways that you use our digital microscopes?
We scan almost all the slides so that we can work with them later with ViewPoint (slide viewer software). For annotations, we use the counting mode, length measurer, and area calculations.
One of the research we conduct is to compare the sterile mice intestines and mice intestines with bacteria. We do immunohistochemical staining, then use the counting mode to see how many cells exist in a specific area. When we view the gut rolls from the mice, we use the measurement tool, either the polyline or line function, to see the length of the colon, villi and ileum. In the case that the mice are inflamed due to an immune reaction or the villi is shortened, it would be possible to see the infiltration of the immune cells to count them.
Previously, we had to take measurements separately from each picture of the microscope slides. Now because we have the overview whole slide image with the M8, there is no need to switch between pictures during annotations. This allows the annotation to be done much quicker.
What’s your favorite part about our microscope?
I like the microscope because it is much easier to handle and you can standardize the scanning process. With the scan function, now I don’t need to sit in front of a microscope forever. The continuous zoom function is also great.